(Ivanhoe Newswire) -- A drug researchers hoped would boost birth rates among women with one of the most common causes of infertility fell short in a new study.
Metformin (Glucophage), which is used to treat diabetes, shown promise in earlier research involving women with polycystic ovary syndrome (PCOS) because it increased the frequency of ovulation. In the new study, however, increased ovulation did not lead to increased births.
In fact, women taking metformin had the lowest birth rates in the study, which compared the drug to the standard drug used to treat infertility in PCOS, clomiphene (Clomid). About a quarter of the women taking clomiphene ended up giving birth, compared to about 7 percent of those taking metformin. Combining the two treatments did not lead to better results, with about a quarter of women again having children.