During exacerbation, vitamin C is markedly decreased in inflammatory diseases, such as acute pneumonia and COPD, according to a new study.
Serbian researchers compared the values of serum ascorbate concentration and laboratory inflammation indicators in 60 nonsmoking patients.
The patients were split into three groups: 20 patients with acute pneumonia (group I), 20 patients with stable COPD (group II), and 20 patients with exacerbated COPD (group III). Researchers concluded that patients in groups I and III had significantly decreased levels of vitamin C and increased inflammation before therapy, compared with patients after therapy.
It is suggested that the elevation of vitamin C in serum is a good prognostic parameter for disease evaluation.